The experimental feasibility of mannitol extraction from olive leaves using super-critical carbon dioxide was investigated. The experimental data indicated that increasing the pressure from 200 to 350 bar and decreasing the temperature from 80 to 40 degrees C resulted in all enhancement of the extraction yield and reduced the partition coefficient significantly. In addition, increasing the extraction time from 10 to 90 min increased the extraction yield, while further increases up to 180 mill did not cause any further change. Ethanol was utilized as all entrainer and the maximum extraction yield was obtained using 20 % of ethanol. Moreover, modeling of the supercritical fluid extraction was carried out with the relevant mass transfer mechanisms involved in the supercritical and solid phases, and the appropriate numerical method of finite difference. The numerical results show that the model with three adjustable parameters is capable of predicting the experimental data very well.