The supercritical fluid elution chromatography process for the removal of undesirable components in petroleum oils could become a viable alternative to conventional solvent extraction or hydrogen treatment used to obtain the mineral oil required for the pharmaceutical and cosmetic industries. In the present paper, we report the results obtained in the removal of undesirable components in a lube oil basestock using different adsorbents and CO, at supercritical conditions of the elution solvent. Data showed the influence of temperature and pressure, mainly in the paraffinic-alkylmonocyclic aromatics separation; for more polar components, the effect of both variables is negligible. The efficiency of studied adsorbents to retain the aromatic and polar compounds at optimum pressure and temperature follows the sequence florisil > alumina > charcoal.