A series of Al-Zr mixed oxides with different molar ratios was prepared by coprecipitation method and characterized by N-2 physiorption, XRD, NH3-TPD and CO2-TPD. Solid solution is formed in the mixed oxides. And the composition of the mixed oxides has significant influence on their acid-base properties. The catalysts were examined with glucose reaction in hot compressed water at 180 A degrees C. The prepared oxides exhibit very good catalytic activity and glucose conversion can be increased from 46.6 to 85%. The products distribution is related with the acid-base property of the oxide.