Poly (trimethylene terephthalate) (PTT) is considered as one of the excellent fiber materials in the twenty-first century. It was synthesized as early as in 1940s, but up to now, it is rather difficult to obtain the PTT with high molecular weight suitable for spinning, due to the absence of highly active catalysts. In this work, two series of catalysts, i.e., xTiO(2)-ZrO2 (x = 6, 8, 10, 15) and SO4 (2-)/xTiO(2)-ZrO2 (x = 6, 8, 10, 15) were prepared, and used for the esterification of terephthalic acid (TPA) and 1,3-Propanediol (PDO). The synthesized catalysts were fully characterized by scanning electron microscope (SEM), infrared diffusion reflectance spectrum (IDRS), X-ray diffraction (XRD) and NH3-temperature programmed desorption (NH3-TPD) techniques. Based on the difference in acidities between xTiO(2)-ZrO2 and SO4 (2-)/xTiO(2)-ZrO2 as indicated by characteristic results of IDRS and NH3-TPD, SO4 (2-)/xTiO(2)-ZrO2 have more Bronsted acid sites on their surfaces than xTiO(2)-ZrO2, as a result, SO4 (2-)/xTiO(2)-ZrO2 had high activities for the esterification of TPA and PDO.