Catalysts from heteropoly acid H3PW12O40 and its Cs, Na, Ba, Pb, Ca, Cd, Cr, Mn, V, La salts supported on clinoptilolite, alumosilicate are highly active in oxidative conversion of propane-butane (OCPB) mixture and formation of C-2-C-4 olefins, oxygen-containing compounds at temperatures T = 100-800 A degrees C. Optimum yields of ethylene and propylene are achieved on heteropoly acid its Cs and Cr salts. The processes of oxidative dehydrogenation (ODPB) and cracking are concurrent in formation of olefins. High activity is caused by dispersity of supported catalysts (XRD, IRS) both formation of crystal hydrates and an amorphous phase of heteropoly acid in a condition of interaction with the carrier.