A variety of flow regimes may be observed in the hydrotransport of solids. Maintaining a consistent operation requires rapid detection of any change in flow regime. The objective of this study was to develop reliable, non-intrusive, and on-line methods for flow regime detection in a hydrotransport pipe based on acoustic measurements. Slurries were transported in a 0.05 m diameter stainless steel hydrotransport pipe. Acoustic measurements were recorded by microphones along the length of the horizontal pipe. Two flow regimes were observed: suspended solids flow and flow over settled solids. Cycle and frequency analyses of the acoustic signals provided reliable identification of these flow regimes.