Porous silicon solid supports with pore diameter 0.5-1 mu m, infiltrated with Ag nanostructures for surface enhanced Raman scattering (SERS) were prepared according to two procedures: spontaneous Ag+ reduction on the surface of freshly etched porous silicon immersed in Ag+ aqueous solutions, or anchoring colloidal Ag nanoparticles on the surface previously functionalized by aminosilane. Using Rhodamine 6G (RH6G) as analyte the detection limits were of the order of 20 mu M and 20 nM with porous silicon metalized by the first and second procedure, respectively. This large increase of sensitivity notwithstanding a reduced surface density of Rhodamine 6G obtained on porous silicon metalized by the second procedure is discussed in terms of better hot spot efficiency and reduced aspecific binding out of the hot regions obtained depositing the colloids on the aminosilane functionalized surface. (C) 2009 Elsevier B. V. All rights reserved.