The effect of several catalysts on coal hydropyrolysis efficiency was studied, having selected catalysts with different characteristics and behaviours. For the experimental conditions used Fe2O3 and ICI 41-6 showed selectivity towards lighter fractions, whilst ZnCl2 led to the highest coal conversion and to the greatest preasphaltenes yields. These results suggested the use of mixtures of catalysts. The heavier molecules of asphaltenes produced as a result of ZnCl2 action, could then be converted into lighter fractions by the action of a selective catalyst. Coal hydropyrolysis tests were undertaken using ZnCl2 mixed with Fe2O3 or ICI 41-6. These mixtures of catalysts led to increased conversions and higher product yields. The best results were obtained in the presence of ZnCl2 mixed with Fe2O3. In an attempt to interpret these results, coal structure before and after swelling pre-treatment was also studied using SEM.