Applied Biochemistry and Biotechnology, Vol.159, No.3, 768-777, 2009
Synthesis and Insecticidal Activity of New 4-Hydroxy-2H-1-benzopyran-2-one Derivatives
Several stable and storable anticoagulant rodenticides involving both merits of acute and chronic rodenticides have been synthesized (Holbrook et al. in Arch Intern Med 165:1095-1106, 2005; Baglin et al. in Br J Haematol 132:277-285, 2006). The structures of synthesized compounds were confirmed by IR, H-1 NMR. The compounds were also evaluated for their anticoagulant and acute biologic activity (Lipton et al., JAMA 252:3004-3005, 3).
Keywords:Anticoagulant rodenticide;4-Hydroxy-2H-1-benzopyran-2-one;Cinnamoyl chloride;4-Bromodiphenyl;Synthesis