화학공학소재연구정보센터
Applied Biochemistry and Biotechnology, Vol.159, No.1, 199-207, 2009
Syntheses of Retinol Glycosides Using beta-glucosidase in SCCO2 Media
beta-Glucosidase isolated from sweet almond catalyzed syntheses of water soluble retinol glycosides were carried out in SCCO2 media with carbohydrates-D-glucose 2, D-galactose 3, D-mannose 4, D-fructose 5, and D-sorbitol 6. Retinol glycosides yields were in the 9-34% range. Reaction with D-fructose 5 gave a highest yield of 34%. Excellent regioselectivity was observed with D-mannose 4 and D-sorbitol 6 which gave exclusively C1 beta-mannoside and C1-D-sorbitolide.