Advanced Materials, Vol.20, No.14, 2751-2751, 2008
Ultrathin coatings with change in reactivity over time enable functional in vitro networks of insect neurons
It's just not cricket! A novel coating system that enables covalent attachment of biomolecules in a nonfouling environment without use of additional chemical crosslinkers is presented. Concanavalin A is patterned on the coatings to direct cell adhesion and growth of neurons from the cricket Gryllus bimaculatus and generate functional, patterned in vitro insect neuronal networks for the first time.