The first complex of a transuranium element (tetravalent plutonium) with nucleotide (deoxycytidinemonophosphate, dCMP) was synthesized and structurally characterized. The crystal structure of [Pu-4(NO3)(8)(HdCMP)(4)(H2O)(8)](NO3)(4)center dot 2H(2)0 consists of complex cations [Pu-4(NO3)(8)(HdCMP)(4)(H2O)(8)](4+), NO3- anions, and water molecules. There are two crystallographically independent Pu atoms in the structure, both having similar surroundings. Each of the Pu atoms is coordinated by three O atoms of phosphate groups belonging to three different (HdCMP) anions, two bidentate nitrate anions, and two water molecules, The crystal structure is confirmed by IR and UV/vis/near-IR spectroscopic data.