In this paper, some drawbacks of original kernel independent component analysis (KICA) and support vector machine (SVM) algorithms are analyzed for the purpose of multivariate statistical process monitoring (MSPM). When the measured variables follow non-Gaussian distribution, KICA provides more meaningful knowledge by extracting higher-order statistics compared with PCA and kernel principal component analysis (KPCA). However. in real industrial processes, process variables are complex and are not absolutely Gaussian or non-Gaussian distributed. Any single technique is not sufficient to extract the hidden information. Hence. both KICA (non-Gaussion part) and KPCA (Gaussion part) are used for fault detection in this paper, which combine the advantages of KPCA and KICA to develop a nonlinear dynamic approach to detect fault online compared to other nonlinear approaches. Because SVM is available for classifying faults, it is used to diagnose fault in this paper. For above mentioned kernel methods, the calculation of eigenvectors and support vectors will be time consuming when the sample number becomes large. Hence, some dissimilar data are analyzed in the input and feature space. The proposed approach is applied to the fault detection and diagnosis in the Tennessee Eastman process. Application of the proposed approach indicates that proposed method effectively captures the nonlinear dynamics in the process variables. (C) 2008 Elsevier Ltd. All rights reserved.