The vapour phase epoxidation of propene with nitrous oxide (N2O) was experimentally investigated in a fixed bed reactor using a CsOx/FeOy/SiO2 Catalyst over a broad range of residence times. The influence of feed composition on the conversion and product distribution was determined for the reactants propene, propylene oxide (PO), propionaldehyde (PA), and N2O. The experimental results were used to derive a formal kinetic model to describe the reactions in a network deduced in the first part of this publication [Thommes, T., Zurcher, S., Wix, A., Reitzmann, A., Kraushaar-Czarnetzki, B., 2007. Catalytic vapour phase epoxidation of propene with nitrous oxide as an oxidant: 1. Reaction network and product distribution. Applied Catalysis A 318, 160-169]. Self-inhibition of the propene conversion was observed, and an inhibition of the PO conversion through PO isomerisation products. The N2O concentration has almost no effect on the conversion of propene and PO, but the PA conversion is accelerated significantly through N2O. Propene related and N2O related PO selectivities display opposed dependencies from reactant concentration. The modelling results indicate that coke is predominantly formed from oxygenated products. It is the key issue for future developments to prevent the fast consecutive conversion of PO. (c) 2008 Elsevier Ltd. All rights reserved.