Air-conditioned office buildings are one of the biggest energy consumers of electricity in developed cities in the subtropical climate regions. A good energy policy for the indoor environment should respond to both the needs of energy conservation and the needs for a desirable indoor healthy environment with a reduction in carbon dioxide (CO2) generation. This study evaluates energy implications and the corresponding CO2 generation of some indoor environmental policies for air-conditioned office buildings in the subtropical climate. In particular, the thermal energy consumption in an air-conditioned office building was evaluated by the heat gains through the building fabric, the transport of outdoor fresh air for ventilation, and the heat generated by the occupant and equipment in the space. With the Monte-Carlo sampling technique and the parameters from the existing office building stocks of Hong Kong, the energy consumption profiles of air-conditioned office buildings in Hong Kong were evaluated. Energy consumption profiles were simulated for certain indoor environmental quality (IEQ) policies on indoor air temperature and CO2 concentration settings in the offices, with other building parameters remaining unchanged. The impact assessment and the regression models described in this study may be useful for evaluation of energy performances of IEQ policies. They will also be useful for the promotion of energy-saving measures in air-conditioned office buildings in Hong Kong. This study presented a useful source of references for policymakers, building professionals and end users to quantify the energy and environmental impacts due to an IEQ policy for air-conditioned office buildings. (C) 2007 Elsevier Ltd. All rights reserved.