Outdoor design conditions are important parameters for energy efficiency of buildings. The result of incorrect selection of outdoor design conditions can be dramatic in view of comfort and energy consumption. In this study, the influence of different outdoor design conditions on air conditioning systems is investigated. For this purpose, cooling loads and capacities of air conditioning equipments for a sample building located in Adana, Turkey are calculated using different outdoor design conditions recommended by ASHRAE, the current design data used in Turkey and the daily maximum dry and wet bulb temperatures of July 21st, which is generally accepted as the design day. The cooling coil capacities obtained from the different outdoor design conditions considered in this study are compared with each other. The cost analysis of air conditioning systems is also performed. It is seen that the selection of outdoor design conditions is a very critical step in calculation of the building cooling loads and design capacities of air conditioning equipments. (C) 2007 Elsevier Ltd. All rights reserved.