Journal of the American Chemical Society, Vol.130, No.7, 2158-2158, 2008
Enantioselective direct amination of alpha-cyanoacetates catalyzed by bifunctional chiral Ru and Ir amido complexes
The bifunctional chiral amido Ir complex catalyzed asymmetric electrophilic direct amination of alpha-substituted alpha-cyanoacetates using azodicarboxylates proceeds rapidly to provide the corresponding hydrazine adducts in high yields and with excellent ea values.