Journal of the American Chemical Society, Vol.130, No.2, 416-416, 2008
alpha-amination of nitrogen heterocycles: Ring-fused aminals
Aromatic aminoaldehydes react with cyclic amines to produce ring-fused aminals under thermal conditions. This process applied to two-step syntheses of the quinazolinone alkaloids deoxyvasicinone and rutaecarpine.