This work presents a novel systematic indicator, heuristics, and process model based decision support framework for retrofitting chemical batch processes. The systematic framework considers the identification of improvement opportunities in a batch plant by considering first the product market situation. The batch plant analysis is structured on three levels: the plant, the process, and the unit operation level, respectively. The analysis of these levels is based on indicators which are of various types and specific for each analysis level. These indicators are linked to heuristics which are used to identify the retrofit actions. Finally, for each identified retrofit action the improvement potential is calculated in order to assess its importance. The developed method was successfully applied to a fine chemical batch production facility, and it was able to identify in a systematic way several retrofit actions with significant improvement potential.