Journal of the American Chemical Society, Vol.129, No.33, 10106-10106, 2007
Observation of the coexistence of sodium and calcium ions in a DNA G-quadruplex ion channel
The crystal structure of a DNA quadruplex, d(TGGGGT), crystallized in the presence of calcium and sodium ions, shows the presence of both ions in the central channel of the structure. This was verified by anomalous dispersion maps, which unequivocally showed the presence of calcium ions.