The iterative method labelled correlation-based tuning (CbT) is considered in this paper for tuning linear time-invariant multivariable controllers. The approach allows one to tune some elements of the controller transfer function matrix to satisfy the desired closed-loop performance. while the other elements are tuned to mutually decouple the closed-loop outputs. Decoupling is achieved by decorrelating a given reference with the non-corresponding outputs. The controller parameters are calculated either by solving a correlation equation (decorrelation procedure) or by minimizing a cross-correlation function (correlation reduction). In addition, the preferred way of exciting a 2 x 2 system for CbT is investigated via the accuracy of the estimated controller parameters. It is shown that simultaneous excitation of both reference signals does not improve the accuracy of the estimated controller parameters compared to the case of sequential excitation. In fact, one must choose between low experimental cost (simultaneous excitation) and better accuracy of the estimated parameters (sequential excitation). The theoretical results are illustrated via three simulation Studies. (C) 2007 Elsevier Ltd. All rights reserved.