The present study was undertaken to determine whether the correlation between fatigue and creep established for polyethylene in air could be extended to environmental liquids. Fatigue and creep tests under various conditions of stress, R-ratio (defined as the ratio of minimum to maximum load in the fatigue loading cycle), and frequency were performed in air and in Igepal solutions. The load-displacement curves indicated that stepwise fatigue crack growth in air was preserved in Igepal solutions at 50 degrees C, the temperature specified for the ASTM standard. In air, systematically decreasing the dynamic component of fatigue loading by increasing the R-ratio to R = 1 (creep) steadily increased the lifetime. In contrast, the lifetime in Igepal was affected to a much smaller extent. The fatigue to creep correlation in air was previously established primarily for tests at 21 degrees C. Before testing the correlation in Igepal, it was necessary to establish the correlation in air at 50 degrees C. Microscopic methods were used to verify stepwise crack growth by the sequential formation and breakdown of a craze zone, and to confirm the fatigue to creep correlation. The crack growth rate under various loading conditions was related to the maximum stress and R-ratio by a power law relationship. Alternatively, a strain rate approach, which considered a creep contribution and a fatigue acceleration factor that depended only on strain rate, reliably correlated fatigue and creep in air at 50 degrees C under most loading conditions of stress, R-ratio and frequency. The exceptions were fatigue loading under conditions of R = 0.1 and frequency less than 1 Hz. It was speculated that compression and bending of highly extended craze fibrils were responsible for unexpectedly high crack speeds.