The purpose of this study was to evaluate histologically and compare the healing of three-wall defects using xenogeneic demineralized bone matrix putty (xDBM putty), porous beta-tricalcium phosphate (beta-TCP), or newly developed non-crystalline calcium phosphate glass around submerged SLA (Sand blasted with Large-grit and Acid Etched) surface dental implants in dogs. All of the treatment groups in this study showed no histologic evidence of new bone formation around implants or of bone to implant contact originating from grafted material. No beneficial effects on osseointegration in intrabony defects around implants was attributed to the use of these grafting materials. (c) 2005 Elsevier B.V. All rights reserved.