Remediation of petroleum-contaminated sites is usually a challenging task. It is hard to identify and customize a desired remediation technique or technique-combination into specific on-site conditions due mainly to the difficulties in gaining insight into the complex source and medium conditions in aquifer systems. Moreover, it is exigent to remediate sites where low-permeability soil layers exist. This study presents an integrated approach based on the simulation of a DPVE-aided (dual-phase vacuum extraction aided) remediation process for the identification and customization of desired remediation techniques,as well as its application to a site located in western Canada. Data of the specific site conditions, the forecasted results of contaminant transport, and the scenarios of remediation techniques with different treatment efficiencies are examined. Then the proposed approach was applied to design six remediation alternatives based on combinations of several technologies and the provision of analyses for system designs and costs. The study will help provide decision support for further remediation actions to be taken at the site.