Polymer(Korea), Vol.15, No.2, 170-174, April, 1991
고분자화된 Vesicle의 투과특성
Permeability Characteristics of Polymerized Vesicle
초록
Vinyl기를 두 개 갖고있는 lipid를 합성하여 이것으로부터 고분자화된 vesicle을 합성하였으며, 이것의 투과도를 고분자화 되기 전의 vesicle과 비교하였다. 고분자화된 vesicle이 고분자화되지 않은 vesicle보다 5배이상 투과 속도가 느림이 밝혀졌다. 이것은 본 실험에서 합성한 lipid가 두 개의 vinyl기를 모두 lipid의 꼬리 부근에 갖기 때문에 옆에 있는 lipid뿐만이 아니라, 윗층과 아래층 사이에서도 crosslinking이 충분히 일어났기 때문이라고 생각된다.
Polymerized vesicle was synthesized from a lipid which had two vinyl groups. and permeability of this vesicle was compared with monomeric analog. Permeability of the polymerized vesicle was five times slower than that of monomeric analog. The reason is that the lipid which was used in this experiment had two vinyl groups at tail position in the lipid, and therefore crosslinking was possible between upper layer and lower layer in the vesicle as well as between side by side.
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