Pulsed laser photolysis with resonance fluorescence monitoring of OH radicals was applied at T = 300 +/- 2 K to obtain the rate constants of k(1) = (3.38 +/- 0.60)x10(-12), k(2) = (2.52 +/- 0.44)x10(-13) and k(3) = (1.06 +/- 0.30)x10(-13) cm(3) molecule(-1) s(-1) with 2 sigma precision given for the overall reactions OH + CH3CH2OH (1), OH + CF2HCH2OH (2) and OH + CF3CH2OH (3), respectively. k(2) is the first direct kinetic data for the reaction of OH radicals with CF2HCH2OH reported in the literature.