The deactivation of the H3PW12O40 (HPW) catalyst supported on TiO2 used in the isomerization reaction of alpha-pinene and its regeneration were studied. The regeneration of the deactivated catalyst was carried out with an air flow at 300 and 500degreesC, with an ozone-enriched oxygen flow at 150degreesC and by extraction with solvent and acid treatment. Only the last treatment permitted to recover its activity restoring it in 48% of its initial value.