Reaction Kinetics and Catalysis Letters, Vol.75, No.1, 21-30, 2002
Effect of modifier structure in the enantioselective hydrogenation of 1-phenyl-1,2-propanedione
Three different modifiers, (-)-cinchonidine, 10,11-dihydrocinchonidine and (+)-cinchonine were investigated in the enantioselective hydrogenation of an unsymmetrical dione, 1-phenyl-1,2-propanedione, over a commercial Pt/Al2O3 catalyst. The catalytic activity, as well as the regio- and enantioselectivity in the hydroxyketones and diols formed were compared.