Macromolecular Rapid Communications, Vol.24, No.1, 92-97, 2003
Living cationic polymerizations utilizing an automated synthesizer: High-throughput synthesis of polyoxazolines
Living cationic ring-opening polymerizations of 2-ethyl-2-oxazoline and purification of the resulting polymers were performed utilizing an automated synthetizer. Eight polymers (500 mg scale) as well as 40 polymers (150 mg scale) were synthesized in parallel to investigate the reproducibility and the living character of the polymerizations. The poly(2-ethyl-2-oxazoline)s obtained such were characterized by means of H-1 NMR spectroscopy, MALDI-TOF mass spectrometry and online gel permeation chromatography.
Keywords:automated synthesis;combinatorial materials research;high-throughput experimentation;living cationic polymerization;parallel chemistry;poly(2-oxazoline)s