This paper presents a simple and versatile patterning method to fabricate polymer patterns with different morphologies and sizes by utilizing soft molding. When a patterned elastomeric stamp was placed on the polymer solution dropped on the substrate, the polymer solution will fill into the grooves of the stamp under capillary force. Through the modulation of the polymer concentration, it is possible to produce highly regular and reproducible polymer patterns with tunable morphologies and sizes using the same microscopic patterned mold. The gained polymer patterns can be further transferred to produce second-generation stamps. (c) 2005 Published by Elsevier B.V.