Recently, the technique of in situ adaptive tabulation (ISAT) was proposed to accomplish efficiently the hitherto formidable task of including detailed chemistry in particle methods for turbulent-reactive Rows. This paper addresses the performance issues (accuracy, efficiency, and storage requirements) involved in the implementation of ISAT in a particle-mesh code to solve for the joint probability density function (JPDF) of velocity-frequency-composition. Detailed error-control analysis for a skeletal methane mechanism is performed using a pairwise mixing stirred reactor (PMSR) Lest. The results of the PMSR tests are used to specify the error tolerance for the JPDF simulation of a piloted non-premixed jet flame. We demonstrate that JPDF simulations of realistic turbulent-reactive Bows with detailed chemistry are now possible within reasonable CPU time and storage requirements.