Aqueous phase synthesis of vic-halohydrins from olefins and N-halosuccinimides in the presence of beta-cyclodextrin

Narender M; Reddy MS; Nageswar YD; Rao KR

Journal of Molecular Catalysis A-Chemical, Vol.258, No.1-2, 10-14, 2006

DOI10.1016/j.molcata.2006.05.009 Export Citation

Aqueous phase synthesis of vic-halohydrins from olefins and N-halosuccinimides in the presence of beta-cyclodextrin

Narender M, Reddy MS, Nageswar YD, Rao KR

A series of bromo- and iodohydrins was prepared regioselectively in excellent yields in one-step procedure by treating the corresponding alkenes at room temperature with NBS and NIS respectively in the presence of beta-cyclodextrin in water. (c) 2006 Elsevier B.V. All rights reserved.

Keywords:olefins;N-halosuccinimides;beta-cyclodextrin;bromo- and iodohydrins;water