화학공학소재연구정보센터
Journal of Molecular Catalysis A-Chemical, Vol.216, No.1, 115-119, 2004
Li-X-type zeolite mediated Michael addition of thiols to cyclic enones and its application in the synthesis of 13-thiaprostaglandins
Michael addition of various thiols to cyclic enones in presence of Li-X-type zeolite has been described. 13-Thiaprostaglandins have been synthesized in good yields using substituted hydroxycyclopentenone as the Michael acceptor and arylthiols as Michael donors. (C) 2004 Elsevier B.V. All rights reserved.