Journal of Molecular Catalysis A-Chemical, Vol.214, No.1, 167-174, 2004
Catalytic asymmetric 1,4-conjugate addition of unmodified aldehyde in ionic liquid
In the presence of a catalytic amount of optically active pyrrolidine derivatives derived from L-proline, conjugate addition of an unmodified aldehyde to 3-buten-2-one in [bmim]PF6 was achieved to afford (2S)-5-keto-aldehyde in up to 59% ee. (C) 2004 Elsevier B.V. All rights reserved.