Chemistry Letters, Vol.36, No.2, 314-315, 2007
Carbenoid addition to phenols to give cycloheptatrienols. Stereochemical regulation and ligand-dependent switching of chemoselectivity
Cycloheptatrienols were prepared stereoselectively by the intramolecular Buchner reaction of phenols using a 2,4-pentanediol tether of suitable stereochemistry, where the intrinsically favorable O-H insertion is effectively suppressed.