Chemistry Letters, Vol.35, No.2, 208-209, 2006
Two-parameter analysis of solvent effects on selectivity in chemical reactions: Information of polarity and activation volume at the transition state in organic and enzymatic reactions
The solvent effects on stereoselectivity in the Diels-Alder reaction of cyclopentadiene, the [2 + 2]photodimerization of 2-cyclopentenone, and the enzymatic asymmetrization of prochiral 1,3-propanediols were analyzed by two-parameter treatment using both the dielectric constant and the solubility parameter to show a good linear relationship.