Novel naphthalimide fluorescent sensors selective for certain proteins on basis of non-covalent interactions between enzyme and inhibitor

Cui DW; Qian XH; Liu FY; Zhang R; Yang Q

Chemistry Letters, Vol.34, No.5, 696-697, 2005

DOI10.1246/cl.2005.696 Export Citation

Novel naphthalimide fluorescent sensors selective for certain proteins on basis of non-covalent interactions between enzyme and inhibitor

Cui DW, Qian XH, Liu FY, Zhang R, Yang Q

A non-covalent interactions' concept for proteins' fluorescent sensor of solvent-sensitive naphthalimide dyes was developed on basis of enzyme-inhibitor principle, which could selectively bind certain hydrolases with significant fluorescence enhancements and apparent blue-shifts in emission wavelength.