Chemistry Letters, Vol.33, No.10, 1278-1279, 2004
Microwave assisted facile one-pot synthesis of Re-188-complex using a tetrahydroborate exchange resin. A bifunctional chelating agent for radiopharmaceuticals
A facile one-pot synthesis of Re-188-complex as a bifunctional chelating agent for the preparation of therapeutic radiopharmaceuticals was accomplished with good labeling yields and radiochemical purity by using a tetrahydroborate exchange resin as a reducing agent for a disulfide ligand as well as the [Re-188]perrhenate ion under microwave irradiation.