A novel coordination polymer, [(NA)(ONA) Mn(II)](n) (HNA = nicotinic acid; H(2)ONA = 2-hydroxynicotinic acid) has been hydrothermally synthesized. Its structure is constructed by mixed-ligands and chains of hexa-coordinated Mn(II) linkers: ONA groups bridge Mn ions to give the right-handed and left-handed helical [(ONA)Mn](n) chains running along (010). The helical chains are further held together by NA groups to form a novel 3-D framework.