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Chemistry Letters, Vol.32, No.5, 416-417, 2003
Liposome immobilization on polymer gel particles by in situ formation of covalent linkages
In situ formation of disulfide linkages between liposomes and Sephacryl gel particles both of that were bearing mercapto moieties was demonstrated. The reaction led to immobilization of the liposomes on the gel. The immobilized liposomes could be detached by reductive treatment of the liposome-gel conjugate, and the resulting gel was still capable of further immobilizing liposomes.