화학공학소재연구정보센터
Chemistry Letters, Vol.31, No.3, 380-381, 2002
Direct synthesis of coumarins by Pd(II)-catalyzed reaction of alkoxyphenols and alkynoates
Reaction of alkoxyphenols and alkynoates in the presence of a catalytic amount of Pd(OAc)(2) in trifluoroacetic acid at room temperature gave coumarin derivatives in high yields. This procedure provides a convenient method for direct synthesis of coumarin derivatives under very mild conditions.