Chemistry Letters, Vol.30, No.2, 172-173, 2001
The first total synthesis of a macrocyclic anti-protozoan, LL-Z1640-2
Anti-protozoan, LL-Z1640-2 has been stereoselectively synthesized from D-ribose through Sonogashira coupling, Tsuji hydrogenolysis, and Mukaiyama lactonization.