We have numerically investigated the enhance effect of noise on the energy transduction of molecular machinery. The energy transduction is enhanced with the increase of relative amplitude of the limit-cycle oscillation in polymer chain. And noise can enlarge the relative amplitude through a mechanism of stochastic resonance (SR). In the simulation, two different types of SR, internal signal SR (ISSR) and explicit ISSR (EISSR) are studied, respectively. And the similarity as well as difference between them was presented. The potential application of the enhance effect of energy transduction is then discussed. (C) 2002 Elsevier Science B.V. All rights reserved.