화학공학소재연구정보센터
Journal of Structural Biology, Vol.158, No.2, 188-195, 2007
Density-based score for selecting near-native atomic models of unknown structures
We present a low-resolution density-based scoring scheme for selecting high-quality models from a large pool of lesser quality models. We use pre-configured decoy data sets that contain large numbers of models with different degrees of correctness to evaluate the performance of the strategy. We find that the scoring scheme consistently identifies one of the highest quality models for a wide variety of target structures, resolution ranges, and noise models. Tests with experimental data yield similar results. (c) 2006 Elsevier Inc. All rights reserved.