Journal of Bioscience and Bioengineering, Vol.103, No.2, 200-202, 2007
Expression of a liver-specific function by a hepatoblastoma cell line cocultured with three-dimensional endothelialized tubes in collagen gels
A human hepatoblastoma cell line, Hep G2, showed albumin production activity, a hepatic function, when cocultured with three-dimensional endothelialized tubes in collagen gels. The albumin production rate of the collagen-based liver-like constructs increased with increasing length of the endothelialized tube in the construct.
Keywords:endothelialized tube;three-dimensional configuration;Hep G2;collagen gel;tissue engineering