This study focused on the surface polymerization of nanofiltration membrane to improve the rejection of endocrine disruption chemicals and pharmaceuticals. Methacrylic acid (MA) was used as a monomer to make the membrane surface more hydrophilic and negatively-charged. Then, the NF membrane was further modified using ethylene diamine as a cross-linker and water soluble carbodiimide as a coupling agent. which allows the formation of amide bond between carboxyl group and primary amine group. Finally, succinic acid was used to increase negatively-charged funtional groups on the NF surface. The rejections of micro-organic pollutants for original and modified membranes were compared and discussed in terms of surface properties including hydrophilicity, zeta potential, and effective pore diameter as well as physico-chemical properties of target compounds.