Journal of the American Chemical Society, Vol.129, No.10, 2752-2752, 2007
Design and synthesis of modular oxazoline ligands for the enantioselective chromium-catalyzed addition of allyl bromide to ketones
By systematically evaluating ligand diastereomers using a modular oxazoline template, a new ligand has been identified leading to the discovery of the first example of a chromium-catalyzed enantioselective allylation of ketones using allylic bromides.