가성소다 수용액에서 사린(GB)의 가수분해

이용한; 이종철; 홍대식; Yong-Han Lee; Jong-Chol Lee; Deasik Hong

Korean Chemical Engineering Research, Vol.45, No.2, 172-177, April, 2007

Export Citation

가성소다 수용액에서 사린(GB)의 가수분해

Hydrolysis of Sarin(GB) in Aqueous NaOH Solution

이용한, 이종철^†, 홍대식

국방과학연구소, 305-600 대전시 유성구 유성우체국 사서함 35-1

Yong-Han Lee, Jong-Chol Lee^†, and Deasik Hong

Agency for Defense Development, P.O. Box 35-1, Yuseong-gu, Daejeon 305-600, Korea

E-mail:

초록

신경작용제의 일종인 고농도의 사린(GB)을 무해한 물질로 전환하기 위한 실험 조건을 찾기 위하여 가성소다 수용액으로 가수분해 하였다. 가수분해 반응은 쟈켓이 부착된 소형 반응기에 circulator를 연결하여 사용하고 2.05 당량의 가성소다 용액에 농도 10 wt%의 사린을 주입한 후 각각의 반응온도(50, 70 및 90 ℃)에서 반응 속도 상수를 구하고 이를 이용하여 각 온도에서 GB를 99% 이상 분해하는데 소요되는 가수분해 시간을 예측하였다. 가수분해 실험 결과 GB는 90 ℃에서 1.2 시간 반응하면 99.99% 이상 분해되었으며 주요 분해생성물은 isopropyl methylphosphonate이었다.

The hydrolysis reaction of sarin(GB), one of the nerve agents was studied in aqueous sodium hydroxide(NaOH) solutions to find the experimental conditions which can convert GB into the less toxic compounds. 10 wt% of GB was added into the aqueous NaOH(2.05 eq) in a small-scale jacket-attached reactor connected to a circulator. The reaction rate constants were measured at three temperatures(50, 70 and 90 ℃) and the reaction times required to degrade the material to > 99% were calculated at different temperatures. In this study, 10 wt% of GB was degraded to 99.99% in 1.2hr at 90 ℃ by the aqueous NaOH solution. The major hydrolysate of GB was isopropyl methylphosphonate.

Keywords:Sarin(GB);Chemical Warfare Agent;Hydrolysis;Mass Spectrometry

[References]

Chemical Weapons Convention, Organization for the Prohibition of Chemical Weapons, Home page, http://www.opcw.nl
Row KH, Park YK, Chem. Ind. Technol., 15(2), 125 (1997)
NATO Advanced Research Workshop, Destruction of Chemical Weapons: Report of the NATO Advanced Research Workshop on Destruction of Military Toxic Waste, Naaldwijik, Netherlands, May(1994). http://www.opcw.nl/chemhaz/arwnaal1.htm
Workshop on Advances in the Alternative Demilitarization Technologies, Reston, Virginia, USA (1995)
Lee JC, Kor. Sol. Was. Eng. Soc., 16(3), 217 (1999)
U.S. National Research Council, “Review and Evaluation of Alternative Technologies for Demilitarization of Assembled Chemical Weapons,” National Academic Press, Appendix D, Washington D.C.,U.S.A., 203-228 (1999)
Yang YC, Baker JA, Ward JR, Chem. Rev., 92, 1729 (1992)
Yang YC, Chem. Ind., 9, 334 (1995)
Wagner GW, Yang YC, Ind. Eng. Chem. Res., 41(8), 1925 (2002)
Miller PL, U.S. Patent 6,080,909 (2000)
Beaudry WT, ERDEC-TR-005, APG, U.S.A. (1993)
U.S. National Research Council, “Interim Design Assessment for the Blue Grass Chemical Agent Destruction Pilot Plant,” National Academies Press, Washington D.C.. U.S.A. (2005)
Lee JC, Lee YH, Park H, Choi SJ, HWAHAK KONGHAK, 41(4), 464 (2003)
D’Agostino PA, Hancock JR, Provost LR, J. Chromatogr. A, 912, 291 (2001)
Yoon Y, Choi HH, Chung ST, Choe S, J. Korean Ind. Eng. Chem., 14(8), 1051 (2003)
Read RW, Black RM, J. Chromatogr. A, 862, 169 (1999)
Kanu AB, Haigh PE, Hill HH, Anal. Chim. Acta, 553, 148 (2005)
Lebedev AT, Toxicol. Appl. Pharmacol., 207, S451 (2005)

[Referenced By]

[1] Chemical Weapons Convention, Organization for the Prohibition of Chemical Weapons, Home page, http://www.opcw.nl

[2] Row KH, Park YK, Chem. Ind. Technol., 15(2), 125 (1997)

[3] NATO Advanced Research Workshop, Destruction of Chemical Weapons: Report of the NATO Advanced Research Workshop on Destruction of Military Toxic Waste, Naaldwijik, Netherlands, May(1994). http://www.opcw.nl/chemhaz/arwnaal1.htm

[4] Workshop on Advances in the Alternative Demilitarization Technologies, Reston, Virginia, USA (1995)

[5] Lee JC, Kor. Sol. Was. Eng. Soc., 16(3), 217 (1999)

[6] U.S. National Research Council, “Review and Evaluation of Alternative Technologies for Demilitarization of Assembled Chemical Weapons,” National Academic Press, Appendix D, Washington D.C.,U.S.A., 203-228 (1999)

[7] Yang YC, Baker JA, Ward JR, Chem. Rev., 92, 1729 (1992)

[8] Yang YC, Chem. Ind., 9, 334 (1995)

[9] Wagner GW, Yang YC, Ind. Eng. Chem. Res., 41(8), 1925 (2002)

[10] Miller PL, U.S. Patent 6,080,909 (2000)

[11] Beaudry WT, ERDEC-TR-005, APG, U.S.A. (1993)

[12] U.S. National Research Council, “Interim Design Assessment for the Blue Grass Chemical Agent Destruction Pilot Plant,” National Academies Press, Washington D.C.. U.S.A. (2005)

[13] Lee JC, Lee YH, Park H, Choi SJ, HWAHAK KONGHAK, 41(4), 464 (2003)

[14] D’Agostino PA, Hancock JR, Provost LR, J. Chromatogr. A, 912, 291 (2001)

[15] Yoon Y, Choi HH, Chung ST, Choe S, J. Korean Ind. Eng. Chem., 14(8), 1051 (2003)

[16] Read RW, Black RM, J. Chromatogr. A, 862, 169 (1999)

[17] Kanu AB, Haigh PE, Hill HH, Anal. Chim. Acta, 553, 148 (2005)

[18] Lebedev AT, Toxicol. Appl. Pharmacol., 207, S451 (2005)