Chemical Reviews, Vol.98, No.3, 939-960, 1998
Inorganic mimics of ribonucleases and ribozymes : From random cleavage to sequence-specific chemistry to catalytic antisense drugs
Keywords:PHOSPHATE DIESTER TRANSESTERIFICATION;3＇-TERMINAL MONOPHOSPHATE GROUP;MODIFIED HAMMERHEAD RIBOZYMES;ION-PROMOTED HYDROLYSIS;SITE-SELECTIVE CLEAVAGE;OLIGO-DNA HYBRID;METAL-ION;RNA CLEAVAGE;GENERAL BASE;PHOSPHODIESTER BONDS