This study reports a revised method for determination of the conditional stability constant (K-c) and the equilibrium metal-to-ligand molar ratio ( n) for various metal- dendrimer complexes. The method employs a system containing an ion- exchange resin, a dendrimer, and a metal (Cu2+ or Pb2+) solution. It considers the multi- dentate nature of dendrimers and employs a nonlinear ( Langmuir) isotherm model to interpret the ion exchange isotherm. For its minimal dendrimer uptake, a weak acid cation- exchange resin, IRC- 50, was found most suitable for the study. For complexes of Cu2+ with a homologue of dendrimers with NH2 terminal groups Kc increased from 10(16.2) to 10(36.6), and n increased from 1 to 13 as the generation number rose from 0.0 to 4.0. Kc for complexes of Pb2+ with a generation-1 dendrimer with NH2 terminal groups was 10(17.2) at pH 5, compared to 10(20.9) for complexes of Pb2+ with a generation-1.5 dendrimer with carboxylate terminal groups.